EXPOSED AND SEQUESTERED ANTIGENS IN TESTES AND THEIR PROTECTION BY REGULATORY T CELL-DEPENDENT SYSTEMIC TOLERANCE

Exposed and Sequestered Antigens in Testes and Their Protection by Regulatory T Cell-Dependent Systemic Tolerance

Continuous exposure of tissue antigen (Ag) to the autoantigen-specific regulatory T cells (Treg) is required to maintain Treg-dependent systemic tolerance.Thus, testis autoantigens, previously considered as sequestered, may not be protected by systemic tolerance.We now document that the complete testis antigen sequestration is not valid.The haploid

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Optimization of Thermomechanical Processing of Some Aluminum Alloys by Dimensional Interpolation Method Using the Matlab

This paper presents results of research on optimization of thermomechanical treatment applied to an alloy of the Al-Zn-Mg-Cu system, used in the aviation industry.Optimizing thermomechanical treatment process is based on a mathematical model that establishes the relationships between the main technological parameters Cookie Icing of thermomechanica

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Long span DNA paired-end-tag (DNA-PET) sequencing strategy for the interrogation of genomic structural mutations and fusion-point-guided reconstruction of amplicons.

Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer.While genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach Cookie Icing to identify genomic SVs, the current application of PET sequencing with short insert size DNA can be in

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